SCHEMBL28526247 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PNP	P00491	2/20	0.52

▸	MAPT	P10636	2/20	0.51

▸	BLM	P54132	1/20	0.51

▸	PMP22	Q01453	1/20	0.51

▸	TSHR	P16473	1/20	0.51

▸	NFKB1	P19838	1/20	0.51

▸	ALDH1A1	P00352	1/20	0.50

▸	TLR7	Q9NYK1	8/20	0.48

▸	CYP3A4	P08684	1/20	0.44

▸	PDE7A	Q13946	2/20	0.43

▸	PDE7B	Q9NP56	2/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23202125	1.00	PNP (0.52)	PNPMAPTBLMPMP22TSHR
SCHEMBL28542518	0.83	ALDH1A1 (0.45)	PNPMAPTBLMPMP22TSHR
SCHEMBL20310514	0.80	PNP (0.54)	PNPMAPTBLMPMP22TSHR
SCHEMBL657360	0.80	PNP (0.54)	PNPMAPTBLMPMP22TSHR
SCHEMBL10109648	0.80	PNP (0.54)	PNPMAPTBLMPMP22TSHR
SCHEMBL13351290	0.80	PNP (0.54)	PNPMAPTBLMPMP22TSHR
SCHEMBL657361	0.80	PNP (0.54)	PNPMAPTBLMPMP22TSHR
SCHEMBL13318964	0.80	PNP (0.54)	PNPMAPTBLMPMP22TSHR
SCHEMBL14543297	0.80	PNP (0.54)	PNPMAPTBLMPMP22TSHR
SCHEMBL10117789	0.80	PNP (0.79)	PNPMAPTBLMPMP22TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-112533607-A	TLR7 agonists	普利缪尼治疗学股份有限公司	2021-03-19	—	—	CN	disclosed