Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.38 |
| ▸ | NADK | O95544 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 3/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526247 | 0.83 | PNP (0.52) | ALDH1A1TLR7PNPMAPTBLM | |
| SCHEMBL23202125 | 0.83 | PNP (0.52) | ALDH1A1TLR7PNPMAPTBLM | |
| SCHEMBL3701954 | 0.80 | NADK (0.57) | LMNANADKMAPTPMP22TSHR | |
| SCHEMBL3704527 | 0.80 | NADK (0.57) | LMNANADKMAPTPMP22TSHR | |
| SCHEMBL16695890 | 0.79 | ALDH1A1 (0.65) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL12174030 | 0.79 | ALDH1A1 (0.65) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL20938192 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL9851714 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAALBMAPK1MEN1 | |
| SCHEMBL8692668 | 0.74 | ALDH1A1 (0.38) | ALDH1A1LMNAALBMAPK1MEN1 | |
| SCHEMBL20224892 | 0.72 | LMNA (0.43) | ALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533607-A | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2021-03-19 | — | — | CN | disclosed |