SCHEMBL28526310

SCHEMBL28526310

COc1ccc(COOC(C)(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.53
AGXT P21549 2/20 0.53
APP P05067 5/20 0.47
MAOB P27338 1/20 0.46
CALM1 P0DP23 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
LTA4H P09960 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28260934 0.98 IDO1 (0.52) IDO1AGXTAPPMAOBCALM1
SCHEMBL27455063 0.83 IDO1 (0.67) IDO1AGXTAPPMAOBCALM1
SCHEMBL10884366 0.80 HTT (0.45) IDO1AGXTCALM1HTTSMN1; SMN2
SCHEMBL11639552 0.79 AGXT (0.50) IDO1AGXTMAOBCA1CA2
SCHEMBL15431874 0.79 IDO1 (0.57) IDO1AGXTAPPMAOBCALM1
SCHEMBL8077148 0.79 IDO1 (0.61) IDO1AGXTAPPMAOBCALM1
SCHEMBL375008 0.77 TSHR (0.48) IDO1AGXTCA1CA2CA9
SCHEMBL28162527 0.77 IDO1 (0.59) IDO1AGXTAPPMAOBCALM1
SCHEMBL9286647 0.76 IDO1 (0.48) IDO1AGXTAPPMAOBCALM1
SCHEMBL3036840 0.75 LTA4H (0.69) IDO1AGXTAPPMAOBLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108602917-B Method for in-situ isomerization of polybutadiene 米其林集团总公司 2021-06-29 CN disclosed
CN-108290445-B Peroxide cured tread 米其林集团总公司 2021-06-29 CN disclosed
CN-106795357-B Olefin block composite thermally conductive materials 陶氏环球技术有限责任公司 2021-04-23 CN disclosed
CN-108633280-B Crosslinked foams made from ethylene/alpha-olefin interpolymers 陶氏环球技术有限责任公司 2021-03-26 CN disclosed