Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.61 |
| ▸ | AGXT | P21549 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 5/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3036840 | 0.82 | LTA4H (0.69) | IDO1AGXTAPPMAOBLTA4H | |
| SCHEMBL34413 | 0.80 | IDO1 (0.67) | IDO1AGXTAPPCA12CA1 | |
| SCHEMBL31270 | 0.80 | IDO1 (0.67) | IDO1AGXTAPPCA12CA1 | |
| SCHEMBL2662936 | 0.78 | TP53 (0.42) | IDO1AGXTCA2TAAR1SMN1; SMN2 | |
| SCHEMBL20000873 | 0.78 | APP (0.80) | IDO1AGXTAPPMAOBHTT | |
| SCHEMBL1475481 | 0.78 | IDO1 (0.64) | IDO1AGXTAPPCA12CA1 | |
| Potassium SCHEMBL1477050 | 0.78 | IDO1 (0.64) | IDO1AGXTAPPCA12CA1 | |
| SCHEMBL5020369 | 0.78 | IDO1 (0.52) | IDO1APPCA2CALM1TAAR1 | |
| SCHEMBL12132133 | 0.77 | IDO1 (0.52) | IDO1AGXTAPPMAOBCALM1 | |
| SCHEMBL23872341 | 0.76 | IDO1 (0.61) | IDO1AGXTAPPCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429559-B | Six-arm polyethylene glycol derivative with terminal iso-functionalization and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-112694608-B | Six-arm polyethylene glycol derivative, preparation method and modified biological related substance | 厦门赛诺邦格生物科技股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115010915-B | Nitrogen-branched nine-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance thereof | 厦门赛诺邦格生物科技股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-4051252-A1 | CRYSTALLINE SOLIDS OF 3-PALMITOYL-AMIDO-1,2-PROPANEDIOL AND 3-PALMITOYL-AMIDO-2-HYDROXY-1-DIMETHOXYTRIPHENYLMETHYLETHER-PROPANE AND METHODS OF MAKING AND USING THE SAME | GERON CORPORATION (US) | 2022-09-07 | — | — | EP | disclosed |
| WO-2021086754-A1 | CRYSTALLINE SOLIDS OF 3-PALMITOYL-AMIDO-1,2-PROPANEDIOL AND 3-PALMITOYL-AMIDO-2-HYDROXY-1-DIMETHOXYTRIPHENYLMETHYLETHER-PROPANE AND METHODS OF MAKING AND USING THE SAME | GERON CORPORATION (US) | 2021-05-06 | — | — | WO | disclosed |
| EP-1032565-A1 | METHOD FOR PREPARING DERIVATIVES OF THE TAXOID CLASS | Aventis Pharma S.A. (FR) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999025704-A1 | METHOD FOR PREPARING DERIVATIVES OF THE TAXOID CLASS | AVENTIS PHARMA S.A. (FR) | 1999-05-27 | — | — | WO | disclosed |