Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884455 | 0.83 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28526310 | 0.80 | IDO1 (0.53) | HTTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL11060388 | 0.79 | ALDH1A1 (0.46) | HTTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL28260934 | 0.79 | IDO1 (0.52) | HTTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL11109286 | 0.72 | ALDH1A1 (0.50) | HTTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL27455063 | 0.72 | IDO1 (0.67) | HTTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL3758807 | 0.71 | ALDH1A1 (0.60) | HTTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL28731398 | 0.71 | CES2 (0.53) | NPC1RAB9APOLBSMN1; SMN2FFAR1 | |
| SCHEMBL28162527 | 0.70 | IDO1 (0.59) | HTTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL468287 | 0.70 | HSD17B10 (0.65) | RAB9ASMN1; SMN2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095860-B1 | POLYMERISATION OF VINYL CHLORIDE MONOMER | ICI AUSTRALIA LIMITED (AU) | 1986-10-01 | — | — | EP | disclosed |
| US-4455412-A | LOW TEMPERATURE, VINYL CHLORIDE | ICI AUSTRALIA LIMITED (AU) | 1984-06-19 | — | — | US | disclosed |
| EP-0095860-A2 | Polymerisation of vinyl chloride monomer | ICI AUSTRALIA LIMITED (AU) | 1983-12-07 | — | — | EP | disclosed |