SCHEMBL28526421

SCHEMBL28526421

Cc1ccc(S)c(C)c1O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TRPA1 O75762 2/20 0.39
CYP1A2 P05177 1/20 0.37
PSMD14 O00487 1/20 0.33
COPS5 Q92905 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
ATM Q13315 1/20 0.33
ELANE P08246 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
SENP1 Q9P0U3 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11747820 0.79 TRPA1 (0.39) ALDH1A1TRPA1CYP1A2PSMD14COPS5
SCHEMBL28460155 0.79 TRPA1 (0.39) ALDH1A1TRPA1CYP1A2ATMKDM4E
SCHEMBL436758 0.79 ALDH1A1 (0.43) ALDH1A1TRPA1PSMD14COPS5GABRA1
SCHEMBL29407125 0.77 ALDH1A1 (0.53) ALDH1A1TRPA1CYP1A2GABRA1GABRB2
SCHEMBL15485256 0.77 ALDH1A1 (0.53) ALDH1A1TRPA1CYP1A2GABRA1GABRB2
SCHEMBL23915 0.77 ALDH1A1 (0.53) ALDH1A1TRPA1CYP1A2GABRA1GABRB2
Hydrochloric Acid SCHEMBL3295087 0.77 TRPA1 (0.37) ALDH1A1TRPA1CYP1A2PSMD14COPS5
SCHEMBL11018429 0.76 ALDH1A1 (0.46) ALDH1A1TRPA1CYP1A2GABRA1GABRB2
SCHEMBL577349 0.75 PSMD14 (0.37) ALDH1A1TRPA1CYP1A2PSMD14COPS5
SCHEMBL44351 0.73 ALDH1A1 (0.62) ALDH1A1TRPA1CYP1A2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557865-A Thioether-promoted cysteine-based bioconjugation method 南京工业大学 2023-01-03 CN claimed
CN-117467139-A Intramolecular toughening flame-retardant synergistic silsesquioxane, preparation method and composite material 航天材料及工艺研究所 2024-01-30 CN disclosed
CN-112321477-B 3, 5-dimethyl-4-sulfuryl-1H-pyrrole compound, preparation method and application 中国药科大学 2022-07-12 CN disclosed
WO-2022111202-A1 3,5-DIMETHYL-4-SULFONE GROUP-1H-PYRROLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国药科大学 2022-06-02 WO disclosed
CN-112321477-A 3, 5-dimethyl-4-sulfuryl-1H-pyrrole compound, preparation method and application 中国药科大学 2021-02-05 CN disclosed