Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 1/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26119873 | 0.85 | MAPT (0.64) | CYP19A1RAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL19196715 | 0.85 | CYP19A1 (0.67) | SREBF2CYP19A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL19195871 | 0.84 | SREBF2 (0.79) | SREBF2CYP19A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL19195907 | 0.84 | SREBF2 (0.79) | SREBF2CYP19A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28522859 | 0.83 | RAB9A (0.73) | SREBF2CYP19A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28522962 | 0.81 | CYP19A1 (0.66) | SREBF2CYP19A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL14081497 | 0.81 | SREBF2 (1.00) | SREBF2CYP19A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL4280995 | 0.81 | SREBF2 (1.00) | SREBF2CYP19A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7215184 | 0.81 | KDM4E (0.73) | CYP19A1RAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL28327240 | 0.81 | KDM4E (0.86) | SREBF2RAB9AKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204507-B | Process for producing 2-aryl-4-alkylthiazole compound | 浙江大学 | 2021-03-02 | — | — | CN | disclosed |