Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523720 | 0.83 | PDE10A (0.47) | PDE10ACYP1A2ALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL28910779 | 0.76 | PDE10A (0.47) | PDE10AALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL28535273 | 0.76 | PDE10A (0.48) | PDE10ACYP1A2ALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL28907986 | 0.74 | PDE10A (0.51) | PDE10ACYP1A2CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL28546238 | 0.73 | ALOX5AP (0.48) | PDE10ACYP1A2ALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL28540938 | 0.67 | PDE10A (0.49) | PDE10AALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL28530348 | 0.67 | ALOX5AP (0.48) | PDE10AALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL8881140 | 0.65 | CYSLTR1 (0.55) | PDE10ACYSLTR1CYSLTR2ALOX5GPBAR1 | |
| SCHEMBL9847398 | 0.65 | CYSLTR1 (0.67) | PDE10ACYP1A2CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8621255 | 0.64 | ALOX5 (0.68) | ALOX5APALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384766-B | Quinoline compound and preparation method and application thereof | 广东环境保护工程职业学院 | 2021-02-09 | — | — | CN | disclosed |
| CN-109627232-B | Quinoline compound and preparation method and application thereof | 广东环境保护工程职业学院 | 2021-02-09 | — | — | CN | disclosed |