Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.57 |
| ▸ | WEE1 | P30291 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540961 | 0.92 | CSF1R (0.54) | CSF1RWEE1KITSRCFLT3 | |
| SCHEMBL28538513 | 0.88 | CSF1R (0.58) | CSF1R | |
| SCHEMBL28529959 | 0.86 | CSF1R (0.56) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL28527132 | 0.84 | CSF1R (0.64) | CSF1RWEE1KITSRCFLT3 | |
| SCHEMBL28527640 | 0.81 | CSF1R (0.59) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL28537798 | 0.81 | CSF1R (0.62) | CSF1RWEE1KITSRCFLT3 | |
| SCHEMBL28909928 | 0.80 | CSF1R (0.53) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL28536148 | 0.80 | CSF1R (0.58) | CSF1RWEE1KITSRCFLT3 | |
| SCHEMBL28527347 | 0.79 | CSF1R (0.57) | CSF1R | |
| SCHEMBL4572793 | 0.78 | CSF1R (0.74) | CSF1RKITSRCFLT3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848613-A | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2020-10-30 | — | — | CN | claimed |
| CN-111848613-B | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-111848613-A | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2020-10-30 | — | — | CN | disclosed |