Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537495 | 0.86 | ALDH1A1 (0.35) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28528453 | 0.86 | TDP1 (0.36) | LMNA | |
| SCHEMBL28540666 | 0.84 | HTR2C (0.38) | DDB1CRBNMEN1KMT2A | |
| SCHEMBL28526866 | 0.82 | PARP1 (0.39) | DDB1CRBNMEN1KMT2AALDH1A1 | |
| SCHEMBL28540668 | 0.81 | DDB1 (0.44) | DDB1CRBNMEN1KMT2AKDM4E | |
| SCHEMBL28528607 | 0.75 | KMT2A (0.40) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL28535845 | 0.73 | — | — | |
| SCHEMBL28527345 | 0.73 | — | — | |
| SCHEMBL28907927 | 0.73 | ALDH1A1 (0.32) | ALDH1A1GFER | |
| SCHEMBL16796843 | 0.70 | DDB1 (0.52) | SMN1; SMN2DDB1CRBNLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480112-B | Method for synthesizing substituted dihydrophenanthroline compound | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-112480112-A | Method for synthesizing substituted dihydrophenanthroline compound | 浙江工业大学 | 2021-03-12 | — | — | CN | disclosed |