Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528453 | 0.86 | TDP1 (0.36) | — | |
| SCHEMBL28526867 | 0.86 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL28523534 | 0.85 | DDB1 (0.40) | ALDH1A1SMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL28540666 | 0.84 | HTR2C (0.38) | MEN1NPC1KMT2A | |
| SCHEMBL28540668 | 0.76 | DDB1 (0.44) | KDM4EMEN1NPC1GAAKMT2A | |
| SCHEMBL28528607 | 0.76 | KMT2A (0.40) | ALDH1A1SMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL28907927 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL14458009 | 0.72 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL22201146 | 0.72 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL28535845 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480112-B | Method for synthesizing substituted dihydrophenanthroline compound | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-112480112-A | Method for synthesizing substituted dihydrophenanthroline compound | 浙江工业大学 | 2021-03-12 | — | — | CN | disclosed |