Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540666 | 0.84 | HTR2C (0.38) | DDB1CRBNHTR2CMEN1KMT2A | |
| SCHEMBL28526867 | 0.81 | SMN1; SMN2 (0.34) | DDB1CRBNMEN1KMT2AKDM4E | |
| SCHEMBL28528607 | 0.79 | KMT2A (0.40) | MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8538828 | 0.77 | DDB1 (0.62) | DDB1CRBNHTR2CMEN1KMT2A | |
| SCHEMBL28537495 | 0.76 | ALDH1A1 (0.35) | MEN1KMT2ANPC1KDM4EGAA | |
| SCHEMBL28528453 | 0.74 | TDP1 (0.36) | GPR174 | |
| SCHEMBL7671819 | 0.71 | DDB1 (0.54) | DDB1CRBNHTR2CMEN1KMT2A | |
| SCHEMBL28526866 | 0.71 | PARP1 (0.39) | DDB1CRBNHTR2CMEN1KMT2A | |
| SCHEMBL5681605 | 0.69 | HTR2C (0.48) | DDB1CRBNHTR2CADRA1AMEN1 | |
| SCHEMBL29746300 | 0.69 | GID4 (0.51) | DDB1CRBNHTR2CADRA1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480112-B | Method for synthesizing substituted dihydrophenanthroline compound | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-112480112-A | Method for synthesizing substituted dihydrophenanthroline compound | 浙江工业大学 | 2021-03-12 | — | — | CN | disclosed |