Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527045 | 0.97 | TSHR (0.36) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9MEN1 | |
| SCHEMBL18613472 | 0.95 | MAPT (0.33) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9MEN1 | |
| SCHEMBL24822046 | 0.95 | TOP2A (0.36) | SMN1; SMN2KMT2ACNR1CNR2ALOX15 | |
| SCHEMBL5605635 | 0.95 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9MEN1 | |
| SCHEMBL18613473 | 0.91 | TSHR (0.34) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9TSHR | |
| SCHEMBL28720301 | 0.89 | ALOX5 (0.33) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9MEN1 | |
| SCHEMBL20624632 | 0.87 | ELANE (0.32) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9TSHR | |
| SCHEMBL29626983 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2CNR1CNR2LMNA | |
| SCHEMBL20624670 | 0.86 | TTR (0.31) | SMN1; SMN2CYP1A2CYP2C9TSHRTTR | |
| SCHEMBL18114041 | 0.86 | ELANE (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164657-A | Prodrugs of directed lymphatics | 莫纳什大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-117088931-A | Prodrugs of directed lymphatics | 莫纳什大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-106715456-B | Prodrugs of directed lymphatics | 莫纳什大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-112430250-A | Lymphatic prodrugs | 莫纳什大学 | 2021-03-02 | — | — | CN | disclosed |