Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527043 | 0.95 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2MEN1 | |
| SCHEMBL18613472 | 0.92 | MAPT (0.33) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2MEN1 | |
| SCHEMBL28527045 | 0.92 | TSHR (0.36) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2MEN1 | |
| SCHEMBL24822046 | 0.90 | TOP2A (0.36) | SMN1; SMN2KMT2AALOX15CNR1CNR2 | |
| SCHEMBL18613473 | 0.88 | TSHR (0.34) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2TSHR | |
| SCHEMBL28720301 | 0.86 | ALOX5 (0.33) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2MEN1 | |
| SCHEMBL20624632 | 0.84 | ELANE (0.32) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2TSHR | |
| SCHEMBL5605640 | 0.84 | TSHR (0.33) | CYP1A2CYP2C9SMN1; SMN2TSHRCNR1 | |
| SCHEMBL20624670 | 0.83 | TTR (0.31) | CYP1A2CYP2C9SMN1; SMN2TSHRTTR | |
| SCHEMBL18114041 | 0.83 | ELANE (0.39) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166594-B2 | Antibacterial activity | AVENTIS PHARMA S.A. (FR) | 2007-01-23 | — | — | US | disclosed |
| US-20030149004-A1 | Streptogramin derivatives, their preparation and compositions containing them | AVENTIS PHARMA S.A. | 2003-08-07 | — | — | US | disclosed |
| US-6569854-B1 | Virginamycins | AVENTIS PHARMA S.A. (FR) | 2003-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149004-A1 | Streptogramin derivatives, their preparation and compositions containing them | MRPL21, ABHD5, APEH | ALDH1A1 4296/4885CYP1A2 1181/4885CYP2C9 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.