Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527257 | 1.00 | CA2 (0.42) | CA2CA1MAPTMAPK1PRKCA | |
| SCHEMBL10581135 | 0.96 | MAPT (0.42) | CA2CA1MAPTMAPK1PRKCA | |
| SCHEMBL23016752 | 0.94 | MAPT (0.44) | MAPTMAPK1PRKCAPRKCDTP53 | |
| SCHEMBL4856250 | 0.92 | CA1 (0.45) | CA2CA1MAPTMAPK1CTSK | |
| SCHEMBL5953699 | 0.90 | CA2 (0.46) | CA2CA1MAPTMAPK1LMNA | |
| SCHEMBL4856594 | 0.90 | CA2 (0.46) | CA2CA1MAPTMAPK1LMNA | |
| SCHEMBL10844707 | 0.90 | GPR84 (0.42) | CA2CA1MAPTMAPK1TP53 | |
| SCHEMBL31540501 | 0.89 | MAPT (0.43) | MAPTMAPK1PRKCAPRKCDPRKCE | |
| SCHEMBL5012509 | 0.88 | GPR84 (0.45) | CA2MAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL22005296 | 0.88 | GPR84 (0.45) | CA2MAPTMAPK1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112512590-A | TLR7 peptide conjugates | 阿普罗斯治疗公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-112513031-A | Acid group containing pyrimidine compounds useful for the treatment of diseases associated with the modulation of TLR7 | 阿普罗斯治疗公司 | 2021-03-16 | — | — | CN | disclosed |