Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581135 | 0.98 | MAPT (0.42) | MAPTMAPK1GPR84FFAR1LMNA | |
| SCHEMBL31540501 | 0.95 | MAPT (0.43) | MAPTMAPK1GPR84FFAR1LMNA | |
| SCHEMBL28527257 | 0.94 | CA2 (0.42) | MAPTMAPK1LMNATP53PRKCA | |
| SCHEMBL28527259 | 0.94 | CA2 (0.42) | MAPTMAPK1LMNATP53PRKCA | |
| SCHEMBL2436142 | 0.94 | GPR84 (0.45) | MAPTMAPK1GPR84FFAR1LMNA | |
| SCHEMBL22005296 | 0.94 | GPR84 (0.45) | MAPTMAPK1GPR84FFAR1LMNA | |
| SCHEMBL5013944 | 0.94 | GPR84 (0.45) | MAPTMAPK1GPR84FFAR1LMNA | |
| SCHEMBL21300541 | 0.94 | GPR84 (0.45) | MAPTMAPK1GPR84FFAR1LMNA | |
| SCHEMBL5012509 | 0.94 | GPR84 (0.45) | MAPTMAPK1GPR84FFAR1LMNA | |
| SCHEMBL27891806 | 0.94 | GPR84 (0.45) | MAPTMAPK1GPR84FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |