Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094695 | 0.81 | ALDH1A1 (0.45) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL2653005 | 0.80 | DCUN1D1 (0.49) | ALDH1A1GAASMN1; SMN2CLK4AURKA | |
| SCHEMBL2651782 | 0.79 | DRD1 (0.42) | ALDH1A1GAAHPGDGFERNPC1 | |
| SCHEMBL17626003 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDSCN2A | |
| SCHEMBL4049587 | 0.75 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAHPGDAPOBEC3G | |
| SCHEMBL2652005 | 0.75 | SMN1; SMN2 (0.38) | KDM4EALDH1A1GAAHPGDGFER | |
| SCHEMBL4047558 | 0.75 | DGAT1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2ATM | |
| SCHEMBL403894 | 0.74 | MTOR (0.43) | KDM4EALDH1A1GAASCN2ANPC1 | |
| SCHEMBL27876872 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1GAAHPGDMPI | |
| SCHEMBL6616595 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1GAAHPGDMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396505-A | Methods of treating inflammation | 维鲁公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-115379835-A | Methods of treating coronavirus | 维鲁公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-112512522-A | Compounds for the treatment of triple negative breast and ovarian cancer | 田纳西大学研究基金会 | 2021-03-16 | — | — | CN | disclosed |
| CN-112437664-A | Compounds for the treatment of pancreatic cancer | 田纳西大学研究基金会 | 2021-03-02 | — | — | CN | disclosed |