Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547986 | 0.87 | SLC6A2 (0.47) | CHRNB2CHRNA4AGXTTACR1MEN1 | |
| SCHEMBL6181884 | 0.84 | CHRNB2 (0.63) | CHRNB2CHRNA4AGXTTACR1MEN1 | |
| SCHEMBL28534097 | 0.82 | CHRNB2 (0.45) | CHRNB2CHRNA4AGXTTACR1MEN1 | |
| SCHEMBL28531540 | 0.82 | CHRNB2 (0.45) | CHRNB2CHRNA4MEN1KMT2ALMNA | |
| SCHEMBL28495568 | 0.81 | KDM4E (0.47) | CHRNB2CHRNA4SMN1; SMN2AGXTTACR1 | |
| SCHEMBL14342059 | 0.80 | SMN1; SMN2 (0.49) | CHRNB2CHRNA4SMN1; SMN2AGXTTACR1 | |
| SCHEMBL28531048 | 0.76 | EPHX1 (0.47) | CHRNB2CHRNA4SLC6A4 | |
| SCHEMBL8429381 | 0.76 | IDO1 (0.38) | CHRNB2CHRNA4AGXTSLC6A2SLC6A4 | |
| SCHEMBL120858 | 0.74 | CNR1 (0.42) | AGXTMEN1KMT2ALMNAPOLB | |
| SCHEMBL24554099 | 0.73 | CHRNB2 (0.48) | CHRNB2CHRNA4SMN1; SMN2AGXTTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | disclosed |