SCHEMBL28528133

SCHEMBL28528133

Brc1ccc2ccc3c(N(c4ccccc4)c4ccccc4-c4ccc(-c5ccccc5)cc4)ccc4ccc1c2c43

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15461336 0.92 CASP3 (0.30)
SCHEMBL26431542 0.90 MEN1 (0.31) CYP1A2
SCHEMBL16639341 0.89 CASP3 (0.30)
SCHEMBL29636227 0.89 CASP3 (0.30)
SCHEMBL10354005 0.89 CDK4 (0.31) ALDH1A1CYP1A2
SCHEMBL28528132 0.88 ALDH1A1 (0.32) ALDH1A1MAPK1CYP1A2
SCHEMBL16632662 0.87 CYP1A2 (0.34) ALDH1A1MAPK1CYP1A2
SCHEMBL22256065 0.86 ALDH1A1 (0.33) ALDH1A1MAPK1
SCHEMBL16639330 0.84 RXRA (0.32)
SCHEMBL23572135 0.84 CA12 (0.39) ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112430189-B Pyrene organic electroluminescent material containing aromatic amine substitution 北京夏禾科技有限公司 2024-03-29 CN disclosed
CN-112430189-A Pyrene organic electroluminescent material containing aromatic amine substitution 北京夏禾科技有限公司 2021-03-02 CN disclosed