Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.59 |
| ▸ | CCR1 | P32246 | 7/20 | 0.58 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.49 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.49 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855062 | 0.90 | CCR1 (0.65) | ACHECCR1DDR1MAPK11MAPK14 | |
| SCHEMBL2860444 | 0.90 | CCR1 (0.60) | ACHECCR1DDR1MAPK11MAPK14 | |
| SCHEMBL2854508 | 0.89 | CCR1 (0.62) | ACHECCR1ALDH1A1KDM4EMAPT | |
| SCHEMBL2856181 | 0.87 | CCR1 (0.56) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2855580 | 0.87 | CCR1 (0.62) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2852112 | 0.86 | CCR1 (0.68) | ACHECCR1DDR1MAPK11MAPK14 | |
| SCHEMBL2852015 | 0.86 | CCR1 (0.63) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2855315 | 0.86 | KDM4E (0.65) | CCR1DDR1MAPK11MAPK14DDR2 | |
| SCHEMBL2854244 | 0.84 | ACHE (0.52) | ACHECCR1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2858942 | 0.84 | CCR1 (0.82) | ACHECCR1KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |