Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 9/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854667 | 0.89 | ALDH1A1 (0.55) | CCR1NPSR1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL2854177 | 0.89 | CCR1 (0.58) | CCR1NPSR1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL2852358 | 0.89 | ALDH1A1 (0.48) | CCR1NPSR1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL2859611 | 0.85 | CCR1 (0.53) | CCR1NPSR1MAPTHSP90AA1TRPV1 | |
| SCHEMBL10366449 | 0.85 | MAPT (0.53) | CCR1NPSR1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL2856206 | 0.85 | ALDH1A1 (0.48) | CCR1NPSR1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL2851983 | 0.82 | ALDH1A1 (0.61) | NPSR1MAPTHSP90AA1ALDH1A1MAPK1 | |
| SCHEMBL2862176 | 0.82 | TRPV1 (0.47) | NPSR1MAPTHSP90AA1ALDH1A1MAPK1 | |
| SCHEMBL10364538 | 0.82 | KEAP1 (0.52) | CCR1MAPTALDH1A1TRPV1KDM4E | |
| SCHEMBL10366936 | 0.80 | KEAP1 (0.52) | MAPTALDH1A1KDM4ENR3C1TRPC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |