Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GPR6 | P46095 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852994 | 0.89 | ALDH1A1 (0.56) | ALDH1A1NPSR1HSP90AA1MAPK1TRPM8 | |
| SCHEMBL10366449 | 0.86 | MAPT (0.53) | ALDH1A1NPSR1HSP90AA1MAPK1MAPT | |
| SCHEMBL2854667 | 0.84 | ALDH1A1 (0.55) | ALDH1A1NPSR1HSP90AA1MAPK1MAPT | |
| SCHEMBL2852358 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPSR1HSP90AA1MAPK1MAPT | |
| SCHEMBL2856206 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPSR1HSP90AA1MAPK1MAPT | |
| SCHEMBL2852819 | 0.82 | CCR1 (0.57) | ALDH1A1NPSR1HSP90AA1MAPK1MAPT | |
| SCHEMBL16615747 | 0.82 | ALDH1A1 (0.65) | ALDH1A1NPSR1HSP90AA1MAPK1TRPM8 | |
| SCHEMBL2862176 | 0.79 | TRPV1 (0.47) | ALDH1A1NPSR1HSP90AA1MAPK1MAPT | |
| SCHEMBL10365422 | 0.77 | MAPT (0.67) | ALDH1A1MAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL10366936 | 0.77 | KEAP1 (0.52) | ALDH1A1MAPTPOLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |