Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1374952 | 0.86 | HSD17B10 (0.47) | HSD17B10ITGB3ITGA2BEGLN1KDM4E | |
| SCHEMBL14671192 | 0.83 | ITGB3 (0.51) | HSD17B10ITGB3ITGA2BEGLN1TSHR | |
| SCHEMBL24577895 | 0.82 | KDM4E (0.57) | HSD17B10ITGB3ITGA2BKDM4EALOX15 | |
| SCHEMBL30148840 | 0.80 | HSD17B10 (0.46) | HSD17B10ITGB3ITGA2BKDM4EGLA | |
| SCHEMBL14671161 | 0.79 | ITGB3 (0.53) | HSD17B10ITGB3ITGA2BEGLN1TSHR | |
| SCHEMBL28518764 | 0.79 | HSD17B10 (0.47) | HSD17B10ITGB3ITGA2BGLA | |
| SCHEMBL17792881 | 0.78 | CYP1A2 (0.55) | ITGB3ITGA2BGLACYP2D6S1PR5 | |
| SCHEMBL23774479 | 0.76 | HSD17B10 (0.44) | HSD17B10ITGB3ITGA2BEGLN1TSHR | |
| SCHEMBL14671193 | 0.75 | ITGB3 (0.42) | HSD17B10ITGB3ITGA2BEGLN1TSHR | |
| SCHEMBL20793540 | 0.74 | HSD17B10 (0.42) | HSD17B10ITGB3ITGA2BEGLN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279848-A | Pan-JAKs inhibitor and application thereof | 四川海思科制药有限公司 | 2021-01-29 | — | — | CN | disclosed |