Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL682711 | 0.77 | GAA (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31017418 | 0.76 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28515674 | 0.75 | ALDH1A1 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL683872 | 0.73 | ALDH1A1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3461693 | 0.73 | TP53 (0.43) | KMT2AMEN1POLBSMN1; SMN2GAA | |
| SCHEMBL21816279 | 0.72 | IRAK4 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3459022 | 0.71 | MAPT (0.40) | KMT2AMEN1PKMPOLBSMN1; SMN2 | |
| SCHEMBL19128307 | 0.69 | MAP3K14 (0.34) | KMT2AATMGAAHTTJAK2 | |
| SCHEMBL7354285 | 0.69 | HTR3A (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22148137 | 0.69 | CA12 (0.46) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164582-A | Protease inhibitor, pharmaceutical composition and application thereof | 周龙兴 | 2023-12-05 | — | — | CN | disclosed |
| CN-112074522-B | Compounds as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | 深圳信立泰药业股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-112074522-A | Compounds as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | 深圳信立泰药业股份有限公司 | 2020-12-11 | — | — | CN | disclosed |