Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870706 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KMT2AUSP2CYP3A4MAPK1 | |
| SCHEMBL28528322 | 0.75 | CA12 (0.49) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL22479275 | 0.72 | IRAK4 (0.40) | ALDH1A1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL28391572 | 0.71 | MEN1 (0.40) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL28521561 | 0.71 | RPA1 (0.40) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL20874144 | 0.69 | MTNR1A (0.35) | KMT2ATP53SMN1; SMN2KDM4ERPA1 | |
| SCHEMBL466144 | 0.69 | CYP3A4 (0.60) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL20874132 | 0.68 | KMT2A (0.34) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL28623498 | 0.66 | KMT2A (0.47) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL362125 | 0.65 | ALDH1A1 (0.44) | ALDH1A1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074522-B | Compounds as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | 深圳信立泰药业股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-112074522-A | Compounds as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | 深圳信立泰药业股份有限公司 | 2020-12-11 | — | — | CN | disclosed |