Methane

Methane

SCHEMBL28528436

C.Cc1cccc(CC2CO2)c1N

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.41
ALDH1A1 P00352 2/20 0.39
GLA P06280 1/20 0.39
TAAR1 Q96RJ0 3/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
ATP4A P20648 1/20 0.33
ATP4B P51164 1/20 0.33
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
CYP2A13 Q16696 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CTSB P07858 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27702930 0.98 CD44 (0.42) CD44ALDH1A1GLATAAR1TP53
Methane SCHEMBL27546774 0.84 CD44 (0.38) CD44ALDH1A1TAAR1TP53CYP3A4
SCHEMBL28198362 0.80 PKM (0.42) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL14248992 0.79 ALDH1A1 (0.42) ALDH1A1GLATP53CYP3A4TSHR
SCHEMBL7049331 0.79 ALDH1A1 (0.48) ALDH1A1GLATAAR1TSHRCYP2A13
SCHEMBL31438264 0.79 ALDH1A1 (0.48) ALDH1A1GLATAAR1TSHRCYP2A13
SCHEMBL28335494 0.79 ALDH1A1 (0.48) ALDH1A1GLATAAR1TSHRCYP2A13
SCHEMBL2919613 0.79 CYP3A4 (0.45) CD44ALDH1A1GLATAAR1TP53
SCHEMBL4271405 0.79 G6PD (0.35) ALDH1A1TAAR1TP53CYP3A4TSHR
SCHEMBL3117388 0.78 ALDH1A1 (0.41) ALDH1A1GLATAAR1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112442256-A Epoxy resin-based high polymer material and preparation method and application thereof 南京大学 2021-03-05 CN disclosed