Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | UBE2N | P61088 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 6/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413550 | 0.88 | KDM4E (0.63) | L3MBTL1KDM4EUBE2NHTR6ALOX5 | |
| SCHEMBL22339784 | 0.85 | KDM4E (0.66) | L3MBTL1KDM4EUBE2NHTR6ALOX5 | |
| SCHEMBL6089916 | 0.82 | KDM4E (0.59) | L3MBTL1KDM4EUBE2NHTR6ALOX5 | |
| SCHEMBL22339785 | 0.81 | KDM4E (0.60) | L3MBTL1KDM4EUBE2NHTR6ALOX5 | |
| SCHEMBL3615171 | 0.78 | HTR6 (0.78) | L3MBTL1KDM4EUBE2NHTR6ALOX5 | |
| SCHEMBL18125259 | 0.78 | HTR6 (0.61) | L3MBTL1KDM4EUBE2NHTR6LMNA | |
| SCHEMBL7498766 | 0.77 | L3MBTL1 (0.65) | L3MBTL1KDM4EUBE2NHTR6ALOX5 | |
| SCHEMBL29414776 | 0.77 | AKR1C3 (0.78) | L3MBTL1KDM4EUBE2NHTR6ALOX5 | |
| SCHEMBL13302219 | 0.77 | KDM4E (0.63) | L3MBTL1KDM4EUBE2NHTR6ALOX5 | |
| SCHEMBL12748306 | 0.77 | AKR1C3 (0.78) | L3MBTL1KDM4EUBE2NHTR6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375104-A | Phospholactone indole compound and preparation method thereof | 苏州大学 | 2021-02-19 | — | — | CN | disclosed |