Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15010394 | 0.80 | CRHBP (1.00) | CRHBPCRHR2KEAP1NFE2L2KDM4E | |
| SCHEMBL28532290 | 0.78 | CRHBP (0.64) | CRHBPCRHR2KEAP1NFE2L2KDM4E | |
| SCHEMBL10170806 | 0.76 | ALDH1A1 (0.71) | KDM4EKMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL12336356 | 0.73 | CRHBP (0.43) | CRHBPCRHR2KEAP1NFE2L2KDM4E | |
| SCHEMBL14983351 | 0.71 | ALDH1A1 (0.53) | KDM4EKMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10214298 | 0.69 | MEN1 (0.87) | CRHBPCRHR2KEAP1NFE2L2KDM4E | |
| SCHEMBL14344241 | 0.67 | KMT2A (0.46) | KDM4EKMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL18809011 | 0.67 | NCF1 (0.57) | KDM4EKMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2777957 | 0.67 | CRHBP (0.43) | CRHBPCRHR2KEAP1NFE2L2KDM4E | |
| SCHEMBL2776738 | 0.67 | CRHBP (0.43) | CRHBPCRHR2KEAP1NFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107915687-B | High-efficiency preparation method of polysubstituted phenazine derivative and oxide thereof | 清华大学 | 2021-02-26 | — | — | CN | disclosed |