Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13927483 | 0.83 | HPGD (0.61) | HPGDKDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL3826961 | 0.83 | HPGD (0.61) | HPGDKDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL9737555 | 0.81 | NPC1 (0.64) | HPGDKDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL30566761 | 0.81 | SMN1; SMN2 (0.69) | HPGDKDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL2406430 | 0.81 | SMN1; SMN2 (0.69) | HPGDKDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL29077243 | 0.79 | ALDH1A1 (0.59) | HPGDKDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL11920156 | 0.79 | RAB9A (0.67) | HPGDKDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL27918922 | 0.79 | HPGD (0.64) | HPGDKDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL27475343 | 0.79 | ALDH1A1 (0.59) | HPGDKDM4ETSHRMAPK1PKM | |
| SCHEMBL13915607 | 0.79 | HPGD (0.61) | HPGDKDM4EHSD17B10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645940-A | 1,3, 4-oxadiazole-norfloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-04-13 | — | — | CN | disclosed |
| CN-112480099-A | 1,3, 4-oxadiazole-ciprofloxacin heterozygote and preparation method and application thereof | 广东省微生物研究所（广东省微生物分析检测中心） | 2021-03-12 | — | — | CN | disclosed |