Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | C1R | P00736 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406430 | 0.81 | SMN1; SMN2 (0.69) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL30566761 | 0.81 | SMN1; SMN2 (0.69) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28529043 | 0.79 | HPGD (0.61) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27475343 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11920156 | 0.79 | RAB9A (0.67) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27918922 | 0.79 | HPGD (0.64) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5901255 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL485159 | 0.74 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29256146 | 0.73 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29077285 | 0.73 | L3MBTL1 (0.62) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300932-A1 | N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | GUIZHOU UNIVERSITY (CN) | 2024-09-12 | — | — | US | disclosed |
| WO-2024174317-A1 | N-PHENYLIMINE-CONTAINING DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 贵州大学 | 2024-08-29 | — | — | WO | disclosed |
| CN-116731003-A | N-phenylimine-containing derivative, and preparation method and application thereof | 贵州大学 | 2023-09-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300932-A1 | N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | PNMT, NNMT, PAH | ALDH1A1 780/4885LMNA 2548/4885SMN1; SMN2 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.