SCHEMBL28529280

SCHEMBL28529280

O=C(O)c1ccccc1C(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.60
ATM Q13315 1/20 0.60
HNF4A P41235 1/20 0.60
BCAT2 O15382 1/20 0.59
ALDH1A1 P00352 2/20 0.58
ALOX15 P16050 1/20 0.58
AKR1C3 P42330 3/20 0.57
FABP3 P05413 1/20 0.55
FABP4 P15090 1/20 0.55
FABP5 Q01469 1/20 0.55
KMT2A Q03164 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MEN1 O00255 1/20 0.53
CHRNB2 P17787 1/20 0.52
CHRNB4 P30926 1/20 0.52
CHRNA3 P32297 1/20 0.52
CHRNA4 P43681 1/20 0.52
CDC25A P30304 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5549354 0.91 BCAT2 (0.68) HNF4ABCAT2ALDH1A1FABP3FABP4
SCHEMBL28897597 0.87 AKR1C3 (0.64) CDC25BATMHNF4ABCAT2ALDH1A1
SCHEMBL28864250 0.87 HNF4A (0.51) CDC25BATMHNF4ABCAT2ALDH1A1
SCHEMBL133057 0.87 HNF4A (0.69) CDC25BATMHNF4ABCAT2ALDH1A1
Benzene SCHEMBL1403559 0.87 HNF4A (0.69) CDC25BATMHNF4ABCAT2ALDH1A1
SCHEMBL26624744 0.87 HNF4A (0.69) CDC25BATMHNF4ABCAT2ALDH1A1
Benzene SCHEMBL28480917 0.87 HNF4A (0.69) CDC25BATMHNF4ABCAT2ALDH1A1
SCHEMBL27592177 0.85 BCAT2 (0.59) CDC25BATMHNF4ABCAT2ALDH1A1
SCHEMBL7407371 0.85 HNF4A (0.73) CDC25BATMHNF4ABCAT2ALDH1A1
Fluoride SCHEMBL11030268 0.85 HNF4A (0.67) CDC25BATMHNF4ABCAT2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108008600-B Radiation-sensitive composition 三菱瓦斯化学株式会社 2021-02-09 CN disclosed