SCHEMBL28529318

SCHEMBL28529318

CCCOc1ccc(C(=O)O)c(OCCC)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
HTT P42858 1/20 0.55
ADRB1 P08588 2/20 0.52
ADRB3 P13945 2/20 0.52
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 2/20 0.51
PTPN11 Q06124 2/20 0.50
PDE10A Q9Y233 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
LMNA P02545 1/20 0.49
RARA P10276 1/20 0.48
RARB P10826 1/20 0.48
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
NPY1R P25929 1/20 0.47
NPY2R P49146 1/20 0.47
RAB9A P51151 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7962117 0.93 KDM4E (0.58) KMT2AHTTADRB1ADRB3KDM4E
SCHEMBL1750042 0.93 PTPN11 (0.57) KDM4EALDH1A1PTPN11RARARARB
SCHEMBL8902012 0.92 THRA (0.54) KMT2AHTTADRB1ADRB3KDM4E
SCHEMBL7290141 0.90 KDM4E (0.51) KMT2AADRB1ADRB3KDM4EALDH1A1
SCHEMBL7820620 0.89 PTPN11 (0.64) PTPN11RARBTP53TSHR
SCHEMBL5492191 0.89 PTPN11 (0.64) PTPN11RARBTP53TSHR
SCHEMBL11322929 0.88 KMT2A (0.55) KMT2AHTTKDM4EALDH1A1PTPN11
SCHEMBL8146895 0.88 KMT2A (0.58) KMT2AHTTALDH1A1PTPN11PDE10A
SCHEMBL8218438 0.86 LMNA (0.55) KMT2AKDM4EALDH1A1L3MBTL1LMNA
SCHEMBL1750021 0.85 PPARG (0.61) KDM4EALDH1A1PTPN11RARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375168-B Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field 华南理工大学 2022-03-29 CN disclosed
CN-112375168-A Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field 华南理工大学 2021-02-19 CN disclosed
CN-112342032-A Rod-like polar liquid crystal molecule, preparation method thereof and rod-like polar nematic liquid crystal 华南理工大学 2021-02-09 CN disclosed