Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750021 | 0.94 | PPARG (0.61) | THRATHRBPPARGPPARAALDH1A1 | |
| SCHEMBL28529318 | 0.92 | KMT2A (0.57) | ALDH1A1KMT2AHTTKDM4EPTPN11 | |
| SCHEMBL11237589 | 0.90 | THRA (0.67) | THRATHRBPPARGPPARAPLA2G2A | |
| SCHEMBL12432167 | 0.90 | THRA (0.67) | THRATHRBPPARGPPARAPLA2G2A | |
| SCHEMBL7290141 | 0.89 | KDM4E (0.51) | PPARGPPARAALDH1A1KMT2APLA2G2A | |
| SCHEMBL5232380 | 0.88 | ALDH1A1 (0.53) | THRATHRBPPARGPPARAALDH1A1 | |
| SCHEMBL11775703 | 0.88 | ALDH1A1 (0.53) | THRATHRBPPARGPPARAALDH1A1 | |
| SCHEMBL9525740 | 0.88 | THRA (0.54) | THRATHRBKMT2AKDM4EHIF1A | |
| SCHEMBL1881271 | 0.87 | KDM4E (0.59) | PPARGPPARAALDH1A1KMT2AKDM4E | |
| SCHEMBL4687671 | 0.86 | PARP15 (0.60) | THRATHRBALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |