Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | EPM2A | O95278 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019781 | 0.96 | KDM4E (0.48) | KDM4EEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL29466898 | 0.96 | KDM4E (0.48) | KDM4EEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL30593470 | 0.92 | KDM4E (0.47) | KDM4EEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL18261966 | 0.92 | KDM4E (0.47) | KDM4EEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL12811607 | 0.87 | EPM2A (0.50) | EPM2APTPN2PTPN1PTPN22MAPT | |
| SCHEMBL1615357 | 0.86 | KDM4E (0.64) | KDM4EEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL15226874 | 0.85 | MAPT (0.43) | KDM4EEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL18267526 | 0.85 | KDM4E (0.45) | KDM4EEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL20383998 | 0.84 | KDM4E (0.42) | KDM4EEPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL6558940 | 0.84 | KDM4E (0.61) | KDM4EEPM2APTPN2PTPN1PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390811-B | Dithia-anthrone derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2022-03-04 | — | — | CN | disclosed |
| CN-112390811-A | Dithia-anthrone derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2021-02-23 | — | — | CN | disclosed |