SCHEMBL5019781

SCHEMBL5019781

O=c1c2cc(Br)ccc2sc2ccc(Br)cc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
EPM2A O95278 1/20 0.47
PTPN2 P17706 1/20 0.47
PTPN1 P18031 1/20 0.47
PTPN22 Q9Y2R2 1/20 0.47
MAPT P10636 4/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
RAB9A P51151 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP2A6 P11509 2/20 0.44
HSP90AA1 P07900 1/20 0.43
TLR9 Q9NR96 1/20 0.43
MIF P14174 1/20 0.41
TP53 P04637 1/20 0.41
PIM1 P11309 2/20 0.41
CHEK1 O14757 1/20 0.41
AURKA O14965 1/20 0.41
DAPK3 O43293 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466898 1.00 KDM4E (0.48) KDM4EEPM2APTPN2PTPN1PTPN22
SCHEMBL28529352 0.96 KDM4E (0.46) KDM4EEPM2APTPN2PTPN1PTPN22
SCHEMBL18261966 0.92 KDM4E (0.47) KDM4EEPM2APTPN2PTPN1PTPN22
SCHEMBL30593470 0.92 KDM4E (0.47) KDM4EEPM2APTPN2PTPN1PTPN22
SCHEMBL1615357 0.90 KDM4E (0.64) KDM4EEPM2APTPN2PTPN1PTPN22
SCHEMBL15226874 0.89 MAPT (0.43) KDM4EEPM2APTPN2PTPN1PTPN22
SCHEMBL18267526 0.89 KDM4E (0.45) KDM4EEPM2APTPN2PTPN1PTPN22
SCHEMBL216673 0.85 EPM2A (0.53) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL29432245 0.85 EPM2A (0.53) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL20383998 0.84 KDM4E (0.42) KDM4EEPM2APTPN2PTPN1PTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114247480-B Preparation method and application of dye-based metal organic framework photocatalyst for inert C-H activation 大连理工大学 2022-12-13 CN claimed
CN-114247480-A Preparation method and application of dye-based metal organic framework photocatalyst for inert C-H activation 大连理工大学 2022-03-29 CN claimed
CN-117964635-B Organic luminescent material based on spiro thioxanthene and preparation method and application thereof 大连理工大学 2024-07-05 CN disclosed
CN-118290438-A Diamine precursor, polyimide and transparent polyimide film based on spiro-bisxanthene structure and manufacturing method thereof 大连理工大学 2024-07-05 CN disclosed
CN-117964635-A Organic luminescent material based on spiro thioxanthene and preparation method and application thereof 大连理工大学 2024-05-03 CN disclosed
US-20230050869-A1 THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH TOYO INK SC HOLDINGS CO., LTD. (JP) 2023-02-16 US disclosed
CN-114247480-B Preparation method and application of dye-based metal organic framework photocatalyst for inert C-H activation 大连理工大学 2022-12-13 CN disclosed
CN-114247480-A Preparation method and application of dye-based metal organic framework photocatalyst for inert C-H activation 大连理工大学 2022-03-29 CN disclosed
EP-3902021-A1 THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH Toyo Ink SC Holdings Co., Ltd. (JP) 2021-10-27 EP disclosed
CN-111269420-A High-plane-rigidity thioxanthone polyimide and preparation method and application thereof 湖南工业大学 2020-06-12 CN disclosed
CN-111040160-A Thioxanthone polyimide and preparation method thereof 湖南工业大学 2020-04-21 CN disclosed
US-20160351831-A1 THIOXANTHONE AROMATIC AMINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2016-12-01 US disclosed
US-20160351831-A1 THIOXANTHONE AROMATIC AMINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2016-12-01 US disclosed
EP-2638028-B1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KK (JP) 2016-06-08 EP disclosed
CN-105154067-A Spiro-di-thioxanthene-based small-molecule luminescent material and preparation and application thereof UNIV SOUTH CHINA TECH 2015-12-16 CN disclosed
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-8952367-B2 Thioxanthone compound and organic light emitting element having the same CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
US-20130221340-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-29 US disclosed
WO-2012063751-A1 THIOXANTHONE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160351831-A1 THIOXANTHONE AROMATIC AMINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME NAT1, ACVR1, ACVRL1 KDM4E 2846/4885EPM2A 4133/4885PTPN2 3939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.