Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.67 |
| ▸ | NPC1 | O15118 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944294 | 1.00 | RAB9A (0.67) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL17298750 | 0.86 | RAB9A (0.61) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28527380 | 0.85 | MAPT (0.57) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30944402 | 0.85 | MAPT (0.57) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28527311 | 0.81 | NPC1 (0.43) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30944412 | 0.81 | NPC1 (0.43) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30944368 | 0.81 | RAB9A (0.76) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28520302 | 0.80 | RAB9A (0.62) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30944420 | 0.80 | RAB9A (0.62) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL15834807 | 0.79 | RAB9A (0.58) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | claimed |
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | disclosed |