Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.76 |
| ▸ | NPC1 | O15118 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944331 | 0.86 | MAPT (0.55) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL28529297 | 0.85 | RAB9A (0.88) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL30944411 | 0.85 | RAB9A (0.88) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL28522078 | 0.85 | RAB9A (0.88) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL30944422 | 0.85 | RAB9A (0.88) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL24071962 | 0.85 | RAB9A (0.88) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL30944350 | 0.85 | RAB9A (0.88) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL31419754 | 0.84 | RAB9A (0.72) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL30944356 | 0.84 | RAB9A (0.72) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL24071576 | 0.82 | RAB9A (0.85) | RAB9ANPC1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |