Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527380 | 1.00 | MAPT (0.57) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL28529424 | 0.85 | RAB9A (0.67) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL30944294 | 0.85 | RAB9A (0.67) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL30944331 | 0.81 | MAPT (0.55) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL30944316 | 0.80 | LMNA (0.70) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL30944397 | 0.78 | RAB9A (0.63) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL28535148 | 0.78 | RAB9A (0.63) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL28529049 | 0.78 | RAB9A (0.63) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL30944380 | 0.78 | RAB9A (0.63) | MAPTLMNARAB9ANPC1MEN1 | |
| SCHEMBL30944412 | 0.74 | NPC1 (0.43) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |