Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854499 | 0.92 | ALDH1A1 (0.58) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL2850357 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL2855130 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTPOLBMAPK14LMNA | |
| SCHEMBL2860615 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL2860988 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1GAAPOLB | |
| SCHEMBL2854412 | 0.77 | MEN1 (0.53) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL2854519 | 0.76 | KDM4E (0.53) | ALDH1A1MAPTPOLBLMNATDP1 | |
| SCHEMBL2850026 | 0.76 | KDM4E (0.52) | ALDH1A1MAPTPOLBS1PR1 | |
| SCHEMBL2875267 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTGAAPOLBMAPK14 | |
| SCHEMBL2326321 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MAPTMAPK1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |