Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856793 | 0.93 | KDM4E (0.53) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2860267 | 0.91 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2855130 | 0.91 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL5927559 | 0.90 | KDM4E (0.51) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2854519 | 0.85 | KDM4E (0.53) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2854395 | 0.85 | MAPT (0.51) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2850026 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL5927637 | 0.84 | KDM4E (0.61) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL5926240 | 0.83 | NOS3 (0.52) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL10365407 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |