Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 7/20 | 0.38 |
| ▸ | SCD | O00767 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28523073 | 0.88 | SCD5 (0.42) | SCD5SCDALDH1A1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL21492529 | 0.83 | KLKB1 (0.39) | ALDH1A1POLB | |
| Trifluoroacetic Acid SCHEMBL28530866 | 0.82 | SMN1; SMN2 (0.42) | TAS2R8RIPK1SCD5SCDALDH1A1 | |
| Hydrochloric Acid SCHEMBL28523109 | 0.78 | TAS2R8 (0.40) | TAS2R8RIPK1SCDALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL29279745 | 0.76 | SCD5 (0.47) | SCD5SCDALDH1A1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL28516996 | 0.76 | SMN1; SMN2 (0.39) | SCD5SCDALDH1A1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL28532098 | 0.75 | SCD (0.42) | SCD5SCDALDH1A1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL28530910 | 0.75 | L3MBTL1 (0.44) | SCD5SCDALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL28523046 | 0.74 | TAS2R8 (0.43) | TAS2R8RIPK1MAPTLMNA | |
| SCHEMBL12507027 | 0.74 | KLKB1 (0.39) | ALDH1A1MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |