Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135361 | 0.78 | KMT2A (0.50) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL19748 | 0.77 | KMT2A (0.61) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL400890 | 0.77 | RAB9A (0.77) | RAB9ANPC1CTDSP1KDM4EPOLB | |
| SCHEMBL28181800 | 0.77 | SMN1; SMN2 (0.31) | SMN1; SMN2KMT2A | |
| SCHEMBL10042096 | 0.75 | KDM4E (0.40) | KDM4ESMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL12324391 | 0.74 | RAB9A (0.82) | RAB9ANPC1CTDSP1KDM4EPOLB | |
| SCHEMBL10518959 | 0.74 | KMT2A (0.34) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL696662 | 0.74 | KMT2A (0.58) | RAB9ANPC1HPGDCYP2C9MEN1 | |
| SCHEMBL11256292 | 0.74 | F2 (0.33) | RAB9ANPC1PTGS2SMN1; SMN2GAA | |
| SCHEMBL466479 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-113307772-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-106257976-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-02-02 | — | — | CN | disclosed |