Sugi Predict

Sugi Predict / Compounds / SCHEMBL19748

SCHEMBL19748

SCHEMBL19748

O=C(Nc1ccccc1)c1cc[nH]n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.61
▸ POLB P06746 1/20 0.58
▸ RAB9A P51151 5/20 0.51
▸ NPC1 O15118 4/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ SMN1; SMN2 Q16637 5/20 0.50
▸ NFKB1 P19838 1/20 0.50
▸ NFKB2 Q00653 1/20 0.50
▸ RELA Q04206 1/20 0.50
▸ CDK2 P24941 2/20 0.47
▸ CCNA2 P20248 1/20 0.47
▸ FLT3 P36888 1/20 0.47
▸ CCNA1 P78396 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.46
▸ CNR1 P21554 1/20 0.46
▸ KDR P35968 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28118358 0.92 KMT2A (0.54) KMT2APOLBRAB9ANPC1ALDH1A1
SCHEMBL6532295 0.90 PTPN1 (0.53) KMT2APOLBRAB9ANPC1ALDH1A1
SCHEMBL6532409 0.86 MGLL (0.55) KMT2APOLBCNR1
SCHEMBL5906988 0.85 KDR (0.54) KMT2APOLBRAB9ANPC1KDM4E
SCHEMBL23246023 0.84 NPC1 (0.53) KMT2ARAB9ANPC1ALDH1A1KDM4E
SCHEMBL11041868 0.84 KDM4E (0.55) KMT2AALDH1A1KDM4EL3MBTL1HTT
SCHEMBL18027798 0.83 RAB9A (0.54) POLBRAB9ANPC1ALDH1A1KDM4E
SCHEMBL168618 0.83 MEN1 (0.63) KMT2ARAB9ANPC1ALDH1A1KDM4E
SCHEMBL16692723 0.83 KMT2A (0.44) KMT2APOLBRAB9ANPC1ALDH1A1
SCHEMBL11039238 0.82 LMNA (0.58) KMT2ARAB9ANPC1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621144-A Cyano-substituted phenyl pyrazole amide derivative and preparation method and application thereof 南开大学 2022-06-14 — — CN claimed
CN-112939866-A Fluorine-substituted phenyl pyrazole amide derivative and preparation method and application thereof 南开大学 2021-06-11 — — CN claimed
CN-104628646-B N-pyrazolyl formanilide compound, intermediate, composition, preparation method and application 中国科学院上海有机化学研究所 2017-11-07 — — CN claimed
CN-105315277-A Chiral bisamide derivatives and preparation and application thereof UNIV NANKAI 2016-02-10 — — CN claimed
CN-103467380-B Substituted phenyl pyrazole amide derivative and preparation method and application thereof UNIV NANKAI 2015-06-24 — — CN claimed
EP-1856055-B1 PYRAZOLE CARBOXYLIC ACID ANILIDES, METHOD FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THEM FOR CONTROLLING PATHOGENIC FUNGI BASF SE (DE) 2014-10-01 — — EP claimed
US-20140128617-A1 METHOD FOR PRODUCING PYRAZOLYLCARBOXANILIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-05-08 — — US claimed
CN-103619822-A Method for producing pyrazolylcarboxanilides BAYER IP GMBH 2014-03-05 — — CN claimed
CN-103467380-A Substituted phenyl pyrazole amide derivative and preparation method and application thereof UNIV NANKAI 2013-12-25 — — CN claimed
EP-1925613-B1 SUBSTITUTED PYRAZOLECARBOXYLIC ACID ANILIDE DERIVATIVE OR SALT THEREOF, INTERMEDIATE THEREOF, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND USE THEREOF NIHON NOHYAKU CO LTD (JP) 2013-04-10 — — EP claimed
CN-1533380-A N-pyrazolylcarboxanilides as fungicides �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-09-29 — — CN claimed
WO-2004067515-A1 PYRAZOLYL CARBOXANILIDES FOR CONTROLLING UNWANTED MICROORGANISMS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-08-12 — — WO claimed
EP-1414803-A1 PYRAZOLYLCARBOXANILIDES AS FUNGICIDES Bayer CropScience AG (DE) 2004-05-06 — — EP claimed
CN-1130348-C Pyrazole carboxanilide fungicide BAYER AG (DE) 2003-12-10 — — CN claimed
WO-2003070705-A1 DISUBSTITUTED PYRAZOLYL CARBOXANILIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-28 — — WO claimed
WO-2003010149-A1 PYRAZOLYLCARBOXANILIDES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2003-02-06 — — WO claimed
CN-1356985-A Pyrazole carboxanilide fungicide BAYER AG (DE) 2002-07-03 — — CN claimed
US-6369093-B1 Pyrazole carboxanilide fungicide BAYER AKTIENGESELLSCHAFT (DE) 2002-04-09 — — US claimed
EP-1161420-A2 FUNGICIDAL PYRAZOLE CARBOXANILIDES Bayer Aktiengesellschaft (DE) 2001-12-12 — — EP claimed
WO-2000014071-A2 PYRAZOLE CARBOXANILIDE FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2000-03-16 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140128617-A1 METHOD FOR PRODUCING PYRAZOLYLCARBOXANILIDES CYP3A4, AADAC, PPOX KMT2A 1982/4885POLB 1303/4885RAB9A 1977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.