Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14882960 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPK1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL16383438 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPK1MAOBRAB9ANPC1 | |
| SCHEMBL29671005 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPK1MAOBRAB9ANPC1 | |
| SCHEMBL24929014 | 0.81 | TDO2 (0.40) | ALDH1A1MAPK1MAOBRAB9ANPC1 | |
| SCHEMBL30140981 | 0.81 | TDO2 (0.40) | ALDH1A1MAPK1MAOBRAB9ANPC1 | |
| SCHEMBL28506701 | 0.81 | MAOB (0.40) | ALDH1A1MAPK1MAOBRAB9ANPC1 | |
| SCHEMBL5805651 | 0.78 | RAB9A (0.50) | ALDH1A1MAPK1MAOBRAB9ANPC1 | |
| SCHEMBL29398181 | 0.78 | RAB9A (0.50) | ALDH1A1MAPK1MAOBRAB9ANPC1 | |
| SCHEMBL4557550 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPK1MAOBRAB9ANPC1 | |
| SCHEMBL30900954 | 0.78 | MAOB (0.46) | ALDH1A1MAOBRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586255-B | Biphenyl compound and application thereof in preparation of 1, 8-dibromopyrene | 西安穿越光电科技有限公司 | 2021-02-26 | — | — | CN | disclosed |