SCHEMBL2853006

SCHEMBL2853006

[CH]1C([Si](C2=Cc3ccccc3[CH]2)(c2ccccc2)c2ccccc2)=Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941031 0.78 ESR1 (0.33)
SCHEMBL10455779 0.71
SCHEMBL727375 0.71
SCHEMBL2861499 0.71
SCHEMBL727392 0.68 CALM1 (0.32)
SCHEMBL464991 0.68 ALDH1A1 (0.40)
SCHEMBL3686373 0.67
SCHEMBL103831 0.66 NPC1 (0.38)
SCHEMBL17296053 0.66 NR1H2 (0.38)
SCHEMBL3687729 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808850-B2 Method of treating polyolefin MITSUI CHEMICALS INC (JP) 2010-01-13 EP disclosed
EP-0808850-B1 Method of treating polyolefin MITSUI CHEMICALS INC (JP) 2001-09-19 EP disclosed
US-5990272-A HEATING POLYOLEFIN CONTACTED WITH A LIGAND DECOMPOSER TO REMOVE DECOMPOSED METALLOCENE LIGANDS FROM THE POLYOLEFIN MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0808850-A1 Method of treating polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-11-26 EP disclosed
EP-0718323-A2 Ethylene type quaternary copolymer rubber SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-06-26 EP disclosed