SCHEMBL727392

SCHEMBL727392

[CH]1C([Si](Cc2ccccc2)(Cc2ccccc2)C2=Cc3ccccc3[CH]2)=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.32
ALDH1A1 P00352 2/20 0.30
KDM4E B2RXH2 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TSHR P16473 2/20 0.30
IDO1 P14902 1/20 0.30
TP53 P04637 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17296053 0.81 NR1H2 (0.38) CALM1ALDH1A1KDM4ETDP1TP53
SCHEMBL2853006 0.68
SCHEMBL10455779 0.67
SCHEMBL2861499 0.67
SCHEMBL727375 0.67
SCHEMBL3686373 0.67
SCHEMBL7941031 0.65 ESR1 (0.33)
SCHEMBL216993 0.64 CALM1 (0.48) CALM1ALDH1A1KDM4ETDP1TSHR
SCHEMBL9422247 0.63 CALM1 (0.45) CALM1ALDH1A1TDP1TSHRIDO1
SCHEMBL11240991 0.62 CALM1 (0.50) CALM1ALDH1A1TDP1TSHRIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2291419-B1 POLYMACROMONOMER AND PROCESS FOR PRODUCTION THEREOF EXXONMOBIL CHEM PATENTS INC (US) 2013-08-21 EP claimed
US-8431662-B2 Polymacromonomer and process for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-30 US claimed
US-20120309903-A1 Polymacromonomer and Process For Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-12-06 US claimed
US-8283428-B2 Polymacromonomer and process for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-09 US claimed
JP-2011525212-A 2011-09-15 JP claimed
EP-2291419-A2 POLYMACROMONOMER AND PROCESS FOR PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2011-03-09 EP claimed
US-20090318640-A1 Polymacromonomer And Process For Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2009-12-24 US claimed
WO-2009155510-A2 POLYMACROMONOMER AND PROCESS FOR PRODUCTION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-12-23 WO claimed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US claimed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US claimed
EP-1753796-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2007-02-21 EP claimed
WO-2005113622-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-12-01 WO claimed
EP-1558655-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2005-08-03 EP claimed
US-20040220359-A1 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2004-11-04 US claimed
US-20040138392-A1 polyolefin adhesives; to produce reactor blends (also called intimate blends) of various polymers and other polymer compositions. EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-15 US claimed
EP-1268657-B1 METHOD OF PREPARATION OF CROSSLINKED BLENDS OF AMORPHOUS AND CRYSTALLINE POLYMERS EXXONMOBIL CHEM PATENTS INC (US) 2004-07-14 EP claimed
WO-2004046214-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-06-03 WO claimed
EP-1268657-A1 METHOD OF PREPARATION OF CROSSLINKED BLENDS OF AMORPHOUS AND CRYSTALLINE POLYMERS EXXON CHEMICAL PATENTS INC. (US) 2003-01-02 EP claimed
US-6323284-B1 COMBINING ALPHA.-OLEFIN MONOMER CONTAINING 3 OR MORE CARBON ATOMS AND DIOLEFIN MONOMER IN THE PRESENCE OF NON-STEREOSPECIFIC AND STEREOSPECIFIC METALLOCENE CATALYST SYSTEMS TO FORM POLYMER EXXONMOBIL CHEMICAL PATENTS, INC. 2001-11-27 US claimed
WO-2001042351-A1 METHOD OF PREPARATION OF CROSSLINKED BLENDS OF AMORPHOUS AND CRYSTALLINE POLYMERS EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO claimed