SCHEMBL28530197

SCHEMBL28530197

CNC(c1ccccc1)S(=O)(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.55
LMNA P02545 3/20 0.55
ALDH1A1 P00352 2/20 0.55
KDM4E B2RXH2 1/20 0.55
GMNN O75496 1/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
PMP22 Q01453 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
SRC P12931 2/20 0.53
CYP2D6 P10635 2/20 0.44
CHRM2 P08172 1/20 0.44
ADRA1A P35348 1/20 0.44
RGS12 O14924 1/20 0.44
GLA P06280 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8090655 0.79 SRC (0.44) KMT2ALMNAALDH1A1KDM4EGMNN
SCHEMBL10033917 0.78 SRC (0.47) KMT2ALMNAALDH1A1KDM4EGMNN
SCHEMBL17995259 0.78 ALDH1A1 (0.44) KMT2ALMNAALDH1A1KDM4EGMNN
Aniline SCHEMBL9309215 0.75 SRC (0.44) KMT2ALMNAALDH1A1KDM4EGMNN
SCHEMBL15121915 0.73 HIF1A (0.46) KMT2ALMNAALDH1A1KDM4EMAPT
Diphenylacetic Acid SCHEMBL27684713 0.72 SRC (0.55) KMT2ALMNAALDH1A1KDM4EGMNN
SCHEMBL13848475 0.72 NPY2R (0.47) KMT2ALMNAALDH1A1KDM4EPOLB
Diphenylmethanol SCHEMBL6670755 0.71 LMNA (0.55) KMT2ALMNAALDH1A1KDM4EGMNN
SCHEMBL3398714 0.71 SRC (0.54) KMT2ALMNAALDH1A1KDM4EGMNN
SCHEMBL248500 0.71 SRC (0.54) KMT2ALMNAALDH1A1KDM4EGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699072-B Process for the preparation of 7H-pyrrolo [2,3-D ] pyrimidine compounds 硕腾服务有限责任公司 2021-02-26 CN claimed