Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521411 | 0.82 | ENPP2 (0.51) | ENPP2LMNAALDH1A1POLBNPSR1 | |
| SCHEMBL28524257 | 0.78 | ENPP2 (0.46) | ENPP2MAPTMEN1KMT2ACA1 | |
| SCHEMBL28908255 | 0.76 | MRGPRX4 (0.41) | ENPP2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL28529096 | 0.74 | NPC1 (0.42) | ENPP2MAPTMEN1KMT2ACA2 | |
| SCHEMBL29954639 | 0.74 | ENPP2 (0.32) | ENPP2CA1CA2POLB | |
| SCHEMBL28520513 | 0.74 | CA1 (0.41) | ENPP2MAPTCA1CA2NPC1 | |
| SCHEMBL28521420 | 0.72 | ALDH1A1 (0.45) | ENPP2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL28512482 | 0.71 | ENPP2 (0.42) | ENPP2MAPT | |
| SCHEMBL4859209 | 0.70 | MEN1 (0.47) | MAPTMEN1KMT2ANPC1LMNA | |
| SCHEMBL519259 | 0.70 | ENPP2 (0.52) | ENPP2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602834-B | Bruton's tyrosine kinase inhibitor | 北京盛诺基医药科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |