Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520517 | 0.86 | ACHE (0.44) | ENPP2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28521420 | 0.84 | ALDH1A1 (0.45) | MRGPRX4ENPP2KMT2ANPC1RAB9A | |
| SCHEMBL28519536 | 0.81 | USP2 (0.42) | MRGPRX4ENPP2ALDH1A1MAPT | |
| SCHEMBL28524257 | 0.79 | ENPP2 (0.46) | MRGPRX4ENPP2KMT2ANPC1RAB9A | |
| SCHEMBL28530451 | 0.76 | ENPP2 (0.43) | ENPP2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28519499 | 0.73 | RXRA (0.40) | ENPP2NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29954639 | 0.72 | ENPP2 (0.32) | ENPP2POLB | |
| SCHEMBL28521411 | 0.72 | ENPP2 (0.51) | MRGPRX4ENPP2ALDH1A1KDM4EPOLB | |
| SCHEMBL28529096 | 0.70 | NPC1 (0.42) | ENPP2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28520513 | 0.69 | CA1 (0.41) | ENPP2NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602834-B | Bruton's tyrosine kinase inhibitor | 北京盛诺基医药科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |