Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13934037 | 0.75 | TAAR1 (0.42) | AOC3TAAR1KDM4EMAPK1ADRA1A | |
| Hydrochloric Acid SCHEMBL10648230 | 0.69 | AOC3 (0.45) | AOC3KDM4ESMN1; SMN2MAPTDPP4 | |
| SCHEMBL12797846 | 0.69 | GABRA1 (0.36) | AOC3TAAR1MAPTHTR2A | |
| SCHEMBL14999441 | 0.68 | TAAR1 (0.39) | AOC3TAAR1KDM4EL3MBTL1MAPK1 | |
| SCHEMBL30883 | 0.68 | AOC3 (0.55) | AOC3TAAR1KDM4EL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5744084 | 0.67 | DPP4 (0.50) | KDM4EGAAMAPTDPP4 | |
| SCHEMBL165313 | 0.66 | AOC3 (0.58) | AOC3TAAR1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL28100171 | 0.66 | ALDH1A1 (0.45) | AOC3KDM4ESMN1; SMN2MAPK1GAA | |
| SCHEMBL16479303 | 0.66 | ALDH1A1 (0.45) | AOC3KDM4ESMN1; SMN2MAPK1GAA | |
| Hydrochloric Acid SCHEMBL2076075 | 0.65 | AOC3 (0.56) | AOC3KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112512641-A | Method for the local protection of molecules of free radicals and/or atmospheric pollutants generated by exposure to ultraviolet radiation | 比奥尼克莱公司 | 2021-03-16 | — | — | CN | disclosed |